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Cancer and neurologic degeneration in xeroderma pigmentosum: long term follow-up characterises the role of DNA repair

Journal of Medical Genetics · 2010 · Vol. 48(3) · pp. 168–176
Porcia T. BradfordAlisa M. GoldsteinDeborah TamuraSikandar G. KhanTakahiro UedaJohn BoyleKangho OhKyoko ImotoH. InuiS MoriwakiSteffen EmmertK. M. PikeArati RaziuddinTeri M. PlonaJohn J. DiGiovannaMargaret A. TuckerKenneth H. Kraemer

Abstract

This 39 year follow-up study of XP patients indicates a major role of DNA repair genes in the aetiology of skin cancer and neurologic degeneration.

Nonmelanoma Skin Cancer StudiesDNA Repair MechanismsOcular Oncology and TreatmentsXeroderma pigmentosumMedicineSkin cancerCancerMelanomaPopulationDermatologyInternal medicineDNA repairCancer research

MeSH terms

AdolescentAdultAgedChildChild, PreschoolDNA RepairFemaleFollow-Up StudiesHumansInfantMaleMelanomaMiddle AgedRetrospective StudiesSkin Neoplasms
Citations
466
FWCI
12.71
field-weighted impact
References
74
Percentile
99%
vs. same field & year
Citations per year
Cited by
Shining a Light on Xeroderma Pigmentosum
Journal of Investigative Dermatology · 2012 · 526 citations
References
Nonmelanoma skin cancer in the United States: Incidence
Journal of the American Academy of Dermatology · 1994 · 1,117 citations
Incidence Estimate of Nonmelanoma Skin Cancer in the United States, 2006
Archives of Dermatology · 2010 · 1,177 citations
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Cancer and neurologic degeneration in xeroderma pigmentosum: long term follow-up characterises the role of DNA repair · Scinovex