articleTop 10% cited
The Role of Sunlight and DNA Repair in Melanoma and Nonmelanoma Skin Cancer
Archives of Dermatology · 1994 · Vol. 130(8) · pp. 1018–1018
Kenneth H. Kraemer✉(National Institutes of Health)
Abstract
These data suggest that (1) DNA repair plays a major role in the prevention of cutaneous cancers in the general population and (2) sunlight exposure is responsible for the induction of melanoma as well as nonmelanoma skin cancer in patients with XP, although acting by different mechanisms for the two types of skin cancer.
DNA Repair Mechanismsmelanin and skin pigmentationSkin Protection and AgingMedicineSkin cancerXeroderma pigmentosumMelanomaBasal cell carcinomaDermatologyPopulationCancerBasal cellPathology
MeSH terms
AdolescentAdultAge FactorsCarcinoma, Basal CellBasal Cell CarcinomaCarcinoma, Squamous CellChildChild, PreschoolCocarcinogenesisDNA RepairEye NeoplasmsFemaleHumansInfantMale
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Cited by
Cancer and neurologic degeneration in xeroderma pigmentosum: long term follow-up characterises the role of DNA repair
Journal of Medical Genetics · 2010 · 466 citations
Shining a Light on Xeroderma Pigmentosum
Journal of Investigative Dermatology · 2012 · 526 citations
References
Xeroderma pigmentosum. Cutaneous, ocular, and neurologic abnormalities in 830 published cases
Archives of Dermatology · 1987 · 1,072 citations
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