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Understanding diagnostic tests 1: sensitivity, specificity and predictive values

Acta Paediatrica · 2007 · Vol. 96(3) · pp. 338–341
Anthony K Akobeng

Abstract

Sensitivity and specificity are important measures of the diagnostic accuracy of a test but cannot be used to estimate the probability of disease in an individual patient. Positive and negative predictive values provide estimates of probability of disease but both parameters vary according to disease prevalence.

Clinical Laboratory Practices and Quality ControlMeta-analysis and systematic reviewsStatistical Methods in Clinical TrialsPredictive valueMedicinePositive predicative valueDiseaseDiagnostic testPredictive value of testsPopulationSensitivity (control systems)Pre- and post-test probabilityPredictive testing

MeSH terms

HumansPredictive Value of TestsSensitivity and SpecificityPrevalence
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