review Open AccessTop 1% cited
Converging Mechanisms in ALS and FTD: Disrupted RNA and Protein Homeostasis
Neuron · 2013 · Vol. 79(3) · pp. 416–438
Shuo‐Chien Ling(Ludwig Cancer Research)Magdalini Polymenidou(University of California, San Diego)Don W. Cleveland✉(Ludwig Cancer Research)
Amyotrophic Lateral Sclerosis ResearchPrion Diseases and Protein MisfoldingParkinson's Disease Mechanisms and TreatmentsFrontotemporal dementiaAmyotrophic lateral sclerosisC9orf72BiologyTrinucleotide repeat expansionGeneticsNeuroscienceGeneDiseaseCell biology
MeSH terms
Autophagy-Related ProteinsC9orf72 ProteinValosin Containing ProteinAdenosine TriphosphatasesAmyotrophic Lateral SclerosisAnimalsDNA-Binding ProteinsHomeostasisHumansModels, BiologicalMutationProteinsRNAUbiquitinsCell Cycle Proteins
Funding
- Ludwig Institute for Cancer Research
- National Institutes of Health
- National Institute on Aging
Citations
1,800
FWCI
67.79
field-weighted impact
References
261
Percentile
100%
vs. same field & year
Citations per year
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References
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The American Journal of Human Genetics · 2000 · 767 citations
TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
Biochemical and Biophysical Research Communications · 2006 · 2,755 citations
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Molecular Cell · 2009 · 1,481 citations
Pathological TDP‐43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with <i>SOD1</i> mutations
Annals of Neurology · 2007 · 982 citations
p62 positive, TDP-43 negative, neuronal cytoplasmic and intranuclear inclusions in the cerebellum and hippocampus define the pathology of C9orf72-linked FTLD and MND/ALS
Acta Neuropathologica · 2011 · 469 citations
Nomenclature and nosology for neuropathologic subtypes of frontotemporal lobar degeneration: an update
Acta Neuropathologica · 2009 · 1,002 citations
A Mutation in the Vesicle-Trafficking Protein VAPB Causes Late-Onset Spinal Muscular Atrophy and Amyotrophic Lateral Sclerosis
The American Journal of Human Genetics · 2004 · 973 citations
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