article Open AccessTop 1% cited
p62 positive, TDP-43 negative, neuronal cytoplasmic and intranuclear inclusions in the cerebellum and hippocampus define the pathology of C9orf72-linked FTLD and MND/ALS
Acta Neuropathologica · 2011 · Vol. 122(6) · pp. 691–702
Safa Al‐Sarraj✉(King's College Hospital)Andrew King(King's College Hospital)Claire Troakes(King's College London)Bradley Smith(King's College London)Satomi Maekawa(King's College Hospital)István Bódi(King's College Hospital)Boris Rogelj(King's College London)Ammar Al‐Chalabi(King's College London)Tibor Hortobágyi(King's College London)Christopher E. Shaw(King's College London)
Amyotrophic Lateral Sclerosis ResearchParkinson's Disease Mechanisms and TreatmentsNeurogenetic and Muscular Disorders ResearchAmyotrophic lateral sclerosisC9orf72PathologyCerebellumCytoplasmic inclusionHippocampusBiologyGranular layerPurkinje cellCytoplasm
MeSH terms
Sequestosome-1 ProteinC9orf72 ProteinAdultAgedAged, 80 and overAmyotrophic Lateral SclerosisInclusion BodiesCerebellumDNADNA-Binding ProteinsFemaleHippocampusHumansMaleMiddle Aged
Funding
- Medical Research Council
Citations
469
FWCI
29.01
field-weighted impact
References
35
Percentile
100%
vs. same field & year
Citations per year
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References
TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
Biochemical and Biophysical Research Communications · 2006 · 2,755 citations
Nomenclature and nosology for neuropathologic subtypes of frontotemporal lobar degeneration: an update
Acta Neuropathologica · 2009 · 1,002 citations
Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration
Acta Neuropathologica · 2007 · 1,121 citations
A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD
Neuron · 2011 · 4,424 citations
Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS
Neuron · 2011 · 4,922 citations
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