review Open AccessTop 1% cited

The Cancer Stem Cell Niche: How Essential Is the Niche in Regulating Stemness of Tumor Cells?

Cell stem cell · 2015 · Vol. 16(3) · pp. 225–238

Vicki Plaks✉(University of California, San Francisco)Niwen Kong(University of California, San Francisco)Zena Werb(University of California, San Francisco)

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Cancer Cells and Metastasis Cancer Genomics and Diagnostics 3D Printing in Biomedical ResearchBiologyCancer stem cellNicheTumor initiationEcological nicheTumor microenvironmentStem cellPhenotypeCancer researchTumor progression

MeSH terms

AnimalsHumansNeoplasm MetastasisNeoplasmsNeoplastic Stem CellsStem Cell NicheTumor Microenvironment

Funding

China Scholarship Council

Citations

1,561

FWCI

54.03

field-weighted impact

References

164

Percentile

100%

vs. same field & year

Citations per year

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References

The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited

Nature reviews. Cancer · 2003 · 4,647 citations

Tumor-Associated Macrophages: From Mechanisms to Therapy

Immunity · 2014 · 3,967 citations

Cancer Stem Cells—Perspectives on Current Status and Future Directions: AACR Workshop on Cancer Stem Cells

Cancer Research · 2006 · 3,057 citations

Cancer stem cells in solid tumours: accumulating evidence and unresolved questions

Nature reviews. Cancer · 2008 · 3,448 citations

Evolution of the Cancer Stem Cell Model

Cell stem cell · 2014 · 2,215 citations

Matrix Metalloproteinases: Regulators of the Tumor Microenvironment

Cell · 2010 · 4,974 citations