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Predicting Outcome after Traumatic Brain Injury: Development and International Validation of Prognostic Scores Based on Admission Characteristics

PLoS Medicine · 2008 · Vol. 5(8) · pp. e165–e165
Ewout W. SteyerbergNino A. MushkudianiPablo PerelIsabella ButcherJuan LüGillian S. McHughGordon MurrayAnthony MarmarouIan RobertsJ. Dik F. HabbemaAndrew I.R. Maas

Abstract

Prognostic models using baseline characteristics provide adequate discrimination between patients with good and poor 6 mo outcomes after TBI, especially if CT and laboratory findings are considered in addition to traditional predictors. The model predictions may support clinical practice and research, including the design and analysis of randomized controlled trials.

Traumatic Brain Injury and Neurovascular DisturbancesTrauma and Emergency Care StudiesAcute Ischemic Stroke ManagementMedicineGlasgow Coma ScaleTraumatic brain injuryGlasgow Outcome ScaleLogistic regressionReceiver operating characteristicInternal medicineHead injuryArea under the curveEmergency medicine

MeSH terms

AdultBrain InjuriesClinical Trials as TopicHumansMiddle AgedModels, BiologicalPatient AdmissionPrognosisReproducibility of ResultsTrauma Severity IndicesTreatment Outcome

Funding

  • National Institutes of Health
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