article Open AccessTop 1% cited
Aripiprazole, A Novel Atypical Antipsychotic Drug with a Unique and Robust Pharmacology
Neuropsychopharmacology · 2003 · Vol. 28(8) · pp. 1400–1411
Д. А. Шапиро(Case Western Reserve University)Sean M Renock(Case Western Reserve University)Elaine G. Arrington(University of North Carolina at Chapel Hill)Louis A. Chiodo(Texas Tech University Health Sciences Center)Li-Xin Liu(Texas Tech University Health Sciences Center)David R. Sibley(National Institutes of Health)Bryan L. Roth✉(Case Western Reserve University)Richard B. Mailman(University of North Carolina at Chapel Hill)
Receptor Mechanisms and SignalingNeurotransmitter Receptor Influence on BehaviorSchizophrenia research and treatmentAripiprazolePartial agonistDopamine receptor D2Receptor5-HT receptorAgonistPharmacologyChemistryInverse agonistDopamine receptor
MeSH terms
AripiprazoleCyclic AMPDose-Response Relationship, DrugHumansPiperazinesReceptors, DopamineReceptors, SerotoninAntipsychotic AgentsPotassium ChannelsQuinolones
Funding
- National Alliance for Research on Schizophrenia and Depression
- National Institute of Mental Health
Citations
967
FWCI
12.19
field-weighted impact
References
140
Percentile
99%
vs. same field & year
Citations per year
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References
Possible Role of Valvular Serotonin 5-HT2B Receptors in the Cardiopathy Associated with Fenfluramine
Molecular Pharmacology · 2000 · 428 citations
Aripiprazole, a Novel Antipsychotic, Is a High-Affinity Partial Agonist at Human Dopamine D2 Receptors
Journal of Pharmacology and Experimental Therapeutics · 2002 · 915 citations
Aripiprazole in the treatment of schizophrenia: safety and tolerability in short-term, placebo-controlled trials
Schizophrenia Research · 2003 · 469 citations
LIGAND: A versatile computerized approach for characterization of ligand-binding systems
Analytical Biochemistry · 1980 · 8,490 citations
The antipsychotic aripiprazole is a potent, partial agonist at the human 5-HT1A receptor
European Journal of Pharmacology · 2002 · 505 citations
Agonist-receptor efficacy II: agonist trafficking of receptor signals
Trends in Pharmacological Sciences · 1995 · 651 citations
Do Novel Antipsychotics Have Similar Pharmacological Characteristics? A Review of the Evidence
Neuropsychopharmacology · 1998 · 715 citations
Clozapine for the Treatment-Resistant Schizophrenic
Archives of General Psychiatry · 1988 · 4,110 citations
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