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Glycoengineering: The effect of glycosylation on the properties of therapeutic proteins

Journal of Pharmaceutical Sciences · 2005 · Vol. 94(8) · pp. 1626–1635
Angus M. SinclairSteve Elliott
Transgenic Plants and ApplicationsErythropoietin and Anemia TreatmentBlood groups and transfusionErythropoietinImmunogenicityIn vivoGlycosylationPharmacokineticsDarbepoetin alfaPharmacologyBiological activityRecombinant DNAChemistry

MeSH terms

Darbepoetin alfaAnemiaAnimalsAntibody FormationErythropoietinGlycoproteinsGlycosylationHumansRecombinant ProteinsProtein EngineeringLeptin
Citations
461
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74
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Cited by
Delivery of Therapeutic Proteins
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Effects of glycosylation on the stability of protein pharmaceuticals
Journal of Pharmaceutical Sciences · 2008 · 636 citations
References
On the frequency of protein glycosylation, as deduced from analysis of the SWISS-PROT database
Biochimica et Biophysica Acta (BBA) - General Subjects · 1999 · 1,854 citations
ASSEMBLY OF ASPARAGINE-LINKED OLIGOSACCHARIDES
Annual Review of Biochemistry · 1985 · 4,861 citations
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