articleTop 1% cited
Macrophage Depletion Diminishes Lesion Size and Severity in Experimental Choroidal Neovascularization
Investigative Ophthalmology & Visual Science · 2003 · Vol. 44(8) · pp. 3586–3586
Diego G. Espinosa‐Heidmann✉(University of Miami)Iván J. Suñer(University of Miami)Eleut P. Hernandez(University of Miami)Dagoberto Monroy(University of Miami)Karl G. Csaky(National Institutes of Health)Scott W. Cousins(University of Miami)
Abstract
Macrophage depletion using CL(2)MDP-lip reduces size, cellularity, and vascularity of CNV. This observation supports the hypothesis that macrophages contribute to the severity of CNV lesions.
Glaucoma and retinal disordersRetinal Diseases and TreatmentsCorneal surgery and disordersChoroidal neovascularizationMedicineVascularityPathologyMacrophageFlow cytometryPropidium iodideChoroidNeovascularizationCD163
MeSH terms
AnimalsAntimetabolitesCell CountChoroidDextransClodronic AcidDisease Models, AnimalFemaleFlow CytometryFluoresceinsLiposomesMacrophagesMice, Inbred C57BLChoroidal NeovascularizationMice
Citations
411
FWCI
13.82
field-weighted impact
References
44
Percentile
99%
vs. same field & year
Citations per year
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References
Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications
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A role for local inflammation in the formation of drusen in the aging eye
American Journal of Ophthalmology · 2002 · 1,089 citations
Intravitreal triamcinolone acetonide for exudative age related macular degeneration
British Journal of Ophthalmology · 2003 · 496 citations
Macrophages and angiogenesis
Journal of Leukocyte Biology · 1994 · 1,119 citations
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Macrophage Depletion Diminishes Lesion Size and Severity in Experimental Choroidal Neovascularization
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