reviewTop 1% cited
Utility of in vitro drug metabolism data in predicting in vivo metabolic clearance
Biochemical Pharmacology · 1994 · Vol. 47(9) · pp. 1469–1479
J. Brian Houston✉(University of Manchester)
Pharmacogenetics and Drug MetabolismDrug Transport and Resistance MechanismsBiochemical and Molecular ResearchHeLaProgrammed cell deathCell cycleMitosisCell cultureIn vivoCell growthIn vitroCellBiology
MeSH terms
AnimalsBiotransformationPharmaceutical PreparationsMetabolic Clearance RateMicrosomes, LiverPharmacokineticsIn Vitro Techniques
Citations
910
FWCI
22.58
field-weighted impact
References
64
Percentile
100%
vs. same field & year
Citations per year
Cited by
The Prediction of Human Pharmacokinetic Parameters from Preclinical and In Vitro Metabolism Data
Journal of Pharmacology and Experimental Therapeutics · 1997 · 577 citations
References
A physiological approach to hepatic drug clearance
Clinical Pharmacology & Therapeutics · 1975 · 1,877 citations
Preparation of rat liver cells
Experimental Cell Research · 1973 · 1,135 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.