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Synthesis and evaluation of anticancer benzoxazoles and benzimidazoles related to UK-1

Bioorganic & Medicinal Chemistry · 2002 · Vol. 10(12) · pp. 3997–4004

Devinder KumarMelissa R. Jacob(University of Mississippi)Michael B. Reynolds(The University of Texas at Austin)Sean M. Kerwin✉(The University of Texas at Austin)

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Synthesis and biological activity Synthesis and Biological Evaluation Cancer therapeutics and mechanismsChemistryBenzoxazoleChemical synthesisStereochemistryCombinatorial chemistryPharmacologyOrganic chemistryBiochemistryIn vitro

MeSH terms

Anti-Bacterial AgentsAntineoplastic AgentsBenzimidazolesBenzoxazolesCationsCell SurvivalDrug Screening Assays, AntitumorHumansMagnesiumStaphylococcus aureusStructure-Activity RelationshipTumor Cells, CulturedInhibitory Concentration 50

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350

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3.32

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92%

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Cited by

Synthesis and anticancer evaluation of bis(benzimidazoles), bis(benzoxazoles), and benzothiazoles

Bioorganic & Medicinal Chemistry · 2006 · 339 citations

References

A new rapid and simple non-radioactive assay to monitor and determine the proliferation of lymphocytes: an alternative to [3H]thymidine incorporation assay

Journal of Immunological Methods · 1994 · 1,354 citations

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