Scinovex
article Open AccessTop 1% cited

High-speed optical frequency-domain imaging

Optics Express · 2003 · Vol. 11(22) · pp. 2953–2953
Seok‐Hyun YunG. J. TearneyJohannes F. de BoerNicusor IftimiaB. E. Bouma

Abstract

We demonstrate high-speed, high-sensitivity, high-resolution optical imaging based on optical frequency-domain interferometry using a rapidly-tuned wavelength-swept laser. We derive and show experimentally that frequency-domain ranging provides a superior signal-to-noise ratio compared with conventional time-domain ranging as used in optical coherence tomography. A high sensitivity of -110 dB was obtained with a 6 mW source at an axial resolution of 13.5 microm and an A-line rate of 15.7 kHz, representing more than an order-of-magnitude improvement compared with previous OCT and interferometric imaging methods.

Optical Coherence Tomography ApplicationsPhotoacoustic and Ultrasonic ImagingAdvanced Fluorescence Microscopy TechniquesOpticsOptical coherence tomographyInterferometryRangingSensitivity (control systems)Frequency domainLaserWavelengthCoherence (philosophical gambling strategy)Signal-to-noise ratio (imaging)

Funding

  • National Science Foundation
  • Massachusetts General Hospital
  • Consortia for Improving Medicine with Innovation and Technology
Citations
856
FWCI
26.27
field-weighted impact
References
25
Percentile
100%
vs. same field & year
Citations per year
Citation Network

How this paper connects to the literature. Drag to explore, click any node to open that paper.

High-speed optical frequency-domain imaging · Scinovex