reviewTop 1% cited

The role of childhood trauma in the neurobiology of mood and anxiety disorders: preclinical and clinical studies

Biological Psychiatry · 2001 · Vol. 49(12) · pp. 1023–1039

Christine Heim(Emory University)Charles B. Nemeroff✉(Emory University)

Stress Responses and Cortisol Child and Adolescent Psychosocial and Emotional Development Early Childhood Education and DevelopmentAnxietyPsychologyPsychopathologyDepression (economics)MoodMood disordersClinical psychologyNeurotransmitter systemsVulnerability (computing)Neuroscience

MeSH terms

Adrenocorticotropic HormoneAdultAnimalsAnxiety DisordersAnxiety, SeparationBrainChildChild AbuseCorticosteroneCorticotropin-Releasing HormoneDepressive DisorderHumansLife Change EventsMaternal BehaviorNerve Net

Citations

2,756

FWCI

14.19

field-weighted impact

References

160

Percentile

100%

vs. same field & year

Citations per year

Cited by

The Neurobiology of Stress and Development

Annual Review of Psychology · 2006 · 1,934 citations

Epigenetics and the Biological Definition of Gene × Environment Interactions

Child Development · 2010 · 1,206 citations

Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse

Nature Neuroscience · 2009 · 3,453 citations

Decision making under stress: A selective review

Neuroscience & Biobehavioral Reviews · 2012 · 812 citations

Neurobiology and consequences of social isolation stress in animal model—A comprehensive review

Biomedicine & Pharmacotherapy · 2018 · 356 citations

Current research trends in early life stress and depression: Review of human studies on sensitive periods, gene–environment interactions, and epigenetics

Experimental Neurology · 2011 · 984 citations

Physiology and Neurobiology of Stress and Adaptation: Central Role of the Brain

Physiological Reviews · 2007 · 4,670 citations

Effects of early life stress on cognitive and affective function: an integrated review of human literature

Psychopharmacology · 2010 · 1,348 citations

References

MRI-based measurement of hippocampal volume in patients with combat- related posttraumatic stress disorder

American Journal of Psychiatry · 1995 · 1,604 citations

Role of serotonin in the pathophysiology of depression: focus on the serotonin transporter

Clinical Chemistry · 1994 · 923 citations

Developmental traumatology part II: brain development∗∗See accompanying Editorial, in this issue.

Biological Psychiatry · 1999 · 970 citations

Hippocampal volume in women victimized by childhood sexual abuse

Psychological Medicine · 1997 · 917 citations

Morphometric evidence for neuronal and glial prefrontal cell pathology in major depression∗∗See accompanying Editorial, in this issue.

Biological Psychiatry · 1999 · 1,481 citations

Amygdala core nuclei volumes are decreased in recurrent major depression

Neuroreport · 1998 · 470 citations

Hippocampal Volume Reduction in Major Depression

American Journal of Psychiatry · 2000 · 1,660 citations

Magnetic resonance imaging-based measurement of hippocampal volume in posttraumatic stress disorder related to childhood physical and sexual abuse—a preliminary report

Biological Psychiatry · 1997 · 1,280 citations

Citation Network

How this paper connects to the literature. Drag to explore, click any node to open that paper.