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Augmentation of adriamycin, melphalan, and cisplatin cytotoxicity in drug-resistant and -sensitive human ovarian carcinoma cell lines by buthionine sulfoximine mediated glutathione depletion

Biochemical Pharmacology · 1985 · Vol. 34(14) · pp. 2583–2586
Thomas C. HamiltonMargaret A. WinkerKaren G. LouieGerald BatistBrent C. BehrensTakashi TsuruoKaren R. GrotzingerWilma M. McKoyRobert C. YoungRobert F. Ozols
Polyamine Metabolism and ApplicationsBladder and Urothelial Cancer TreatmentsCancer Research and TreatmentsButhionine sulfoximineMelphalanCisplatinGlutathioneCytotoxicityDrug resistanceCell cultureChinese hamster ovary cellCancer researchBiology

MeSH terms

Cell LineCell SurvivalCisplatinDoxorubicinDrug ResistanceDrug SynergismFemaleGlutathioneHumansMelphalanMethionine SulfoximineOvarian NeoplasmsButhionine Sulfoximine
Citations
541
FWCI
10.30
field-weighted impact
References
12
Percentile
99%
vs. same field & year
Citations per year
References
PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT
Journal of Biological Chemistry · 1951 · 317,666 citations
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