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Classification of Age-Related Changes in Lumbar Intervertebral Discs

Spine · 2002 · Vol. 27(23) · pp. 2631–2644
Norbert BoosSabine WeißbachH. RohrbachChristoph WeilerKevin F. SprattMichael Nerlich

Abstract

Histologic disc alterations can reliably be graded based on the proposed classification system providing a morphologic framework for more sophisticated molecular biologic analyses of factors leading to age-related disc changes. Diminished blood supply to the intervertebral disc in the first half of the second life decade appears to initiate tissue breakdown.

Spine and Intervertebral Disc PathologyMusculoskeletal pain and rehabilitationMedical Imaging and AnalysisMedicineCadaveric spasmLumbarSagittal planeIntervertebral discIntervertebral diskPathologyAnatomyDegeneration (medical)Lumbar vertebrae

MeSH terms

AdolescentAdultAgedAged, 80 and overAgingAwards and PrizesCadaverChildChild, PreschoolDemographyFemaleHumansInfantInfant, NewbornIntervertebral Disc
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