reviewTop 1% cited
Quantitative analysis of drug-receptor interactions: I. Determination of kinetic and equilibrium properties
Life Sciences · 1981 · Vol. 29(4) · pp. 313–330
Gregory A. Weiland✉(University of Colorado Health)Perry B. Molinoff(University of Colorado Health)
Chemical Thermodynamics and Molecular StructureReceptor Mechanisms and SignalingChemical Reaction MechanismsChemistryThermodynamicsEnthalpyKinetic energyDissociation constantRadioligandEquilibrium constantGibbs free energyEntropy (arrow of time)Receptor
MeSH terms
Adrenergic beta-AgonistsAdrenergic beta-AntagonistsAnimalsBinding, CompetitiveErythrocytesKineticsMathematicsModels, BiologicalPindololRadioligand AssayReceptors, AdrenergicReceptors, Adrenergic, betaReceptors, DrugThermodynamics
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References
THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS
Annals of the New York Academy of Sciences · 1949 · 19,863 citations
LIGAND: A versatile computerized approach for characterization of ligand-binding systems
Analytical Biochemistry · 1980 · 8,490 citations
Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction
Biochemical Pharmacology · 1973 · 12,855 citations
Simultaneous Determination of Beta-1 and Beta-2-Adrenergic Receptors in Tissues Containing Both Receptor Subtypes
Molecular Pharmacology · 1979 · 421 citations
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