review Open AccessTop 1% cited
Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?
Nature Reviews Drug Discovery · 2011 · Vol. 10(4) · pp. 261–275
Shankar Balasubramanian✉(University of Cambridge)Laurence H. Hurley(University of Arizona)Stephen Neidle(Cancer Research UK)
DNA and Nucleic Acid ChemistryRNA Interference and Gene DeliveryAdvanced biosensing and bioanalysis techniquesDruggabilityPromoterComputational biologyGeneBiologyG-quadruplexSmall moleculeDrug discoveryDNAGenetics
MeSH terms
AnimalsAntineoplastic AgentsHumansNeoplasmsPromoter Regions, GeneticDrug DesignDrug Delivery SystemsG-Quadruplexes
Funding
- Biotechnology and Biological Sciences Research Council
Citations
1,689
FWCI
45.38
field-weighted impact
References
144
Percentile
100%
vs. same field & year
Citations per year
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Organic & Biomolecular Chemistry · 2007 · 761 citations
Kinase Mutations and Imatinib Response in Patients With Metastatic Gastrointestinal Stromal Tumor
Journal of Clinical Oncology · 2003 · 2,287 citations
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