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Allogeneic Blood Transfusion Increases the Risk of Postoperative Bacterial Infection: A Meta-analysis

Gary E. HillWilliam H. FrawleyKarl E. GriffithJohn E. ForestnerJoseph P. Minei

Abstract

These results demonstrate that ABT is an associated and apparently significant and frequently overlooked risk factor for the development of postoperative bacterial infection in the surgical patient. Allogeneic blood transfusion is a greater risk factor in the traumatically injured patient when compared with the elective surgical patient for the development of postoperative bacterial infection.

Blood transfusion and managementSurgical site infection preventionTrauma, Hemostasis, Coagulopathy, ResuscitationMeta-analysisOdds ratioMedicineSubgroup analysisBlood transfusionInternal medicineConfidence intervalIncidence (geometry)Multivariate analysisSurgery

MeSH terms

Bacterial InfectionsHumansImmune TolerancePostoperative ComplicationsRisk FactorsTransplantation ImmunologyTransplantation, HomologousWounds and InjuriesOdds RatioTransfusion Reaction
Citations
557
FWCI
9.08
field-weighted impact
References
51
Percentile
99%
vs. same field & year
Citations per year
Cited by
Predefined Massive Transfusion Protocols are Associated With a Reduction in Organ Failure and Postinjury Complications
The Journal of Trauma: Injury, Infection, and Critical Care · 2009 · 399 citations
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Allogeneic Blood Transfusion Increases the Risk of Postoperative Bacterial Infection: A Meta-analysis · Scinovex