articleTop 1% cited

Clinical management of gastrointestinal stromal tumors: Before and after STI-571

Human Pathology · 2002 · Vol. 33(5) · pp. 466–477

Ronald P. DeMatteo✉(University of Virginia)Michael C. Heinrich(University of Virginia)Wael El‐Rifai(Portland VA Medical Center)George D. Demetri(University of Virginia)

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Gastrointestinal Tumor Research and Treatment Sarcoma Diagnosis and Treatment Gastric Cancer Management and OutcomesGiSTStromal tumorCancer researchTyrosine kinaseReceptor tyrosine kinaseTargeted therapyMedicineGastrointestinal tractImatinibStromal cell

MeSH terms

Imatinib MesylateProto-Oncogene MasAdultAgedAged, 80 and overAntineoplastic AgentsBenzamidesFemaleGastrointestinal NeoplasmsHumansMaleMiddle AgedMutationPiperazinesPyrimidines

Citations

634

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22.49

field-weighted impact

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100%

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Citations per year

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References

Gastrointestinal Stromal Tumors—Value of CD34 Antigen in their Identification and Separation from True Leiomyomas and Schwannomas

The American Journal of Surgical Pathology · 1995 · 560 citations

KIT Extracellular and Kinase Domain Mutations in Gastrointestinal Stromal Tumors

American Journal Of Pathology · 2000 · 646 citations

Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr–Abl positive cells

Nature Medicine · 1996 · 3,643 citations

Gastrointestinal stromal tumors: Recent advances in understanding of their biology

Human Pathology · 1999 · 842 citations

Mutations in Exon 11 of c-Kit Occur Preferentially in Malignant versus Benign Gastrointestinal Stromal Tumors and Do Not Occur in Leiomyomas or Leiomyosarcomas

American Journal Of Pathology · 1999 · 550 citations

Abl Protein-Tyrosine Kinase Inhibitor STI571 Inhibits In Vitro Signal Transduction Mediated by c-Kit and Platelet-Derived Growth Factor Receptors

Journal of Pharmacology and Experimental Therapeutics · 2000 · 1,280 citations

Two Hundred Gastrointestinal Stromal Tumors

Annals of Surgery · 2000 · 2,530 citations

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