review Open AccessTop 1% cited
Oral drug delivery with polymeric nanoparticles: The gastrointestinal mucus barriers
Advanced Drug Delivery Reviews · 2011 · Vol. 64(6) · pp. 557–570
Laura M. Ensign✉(Johns Hopkins Medicine)Richard A. Cone(Johns Hopkins Medicine)Justin Hanes✉(Johns Hopkins University)
Advanced Drug Delivery SystemsCarbohydrate Chemistry and SynthesisDrug Solubulity and Delivery SystemsMucusDrug deliveryDrugBioavailabilityGastrointestinal tractPharmacologyDrug carrierChemistryMedicineBiology
MeSH terms
Administration, OralAnimalsBiological AvailabilityDrug StabilityGastric MucosaHumansIntestinal MucosaPolymersSolubilityDrug DesignDrug Delivery SystemsGastrointestinal TractNanoparticles
Citations
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References
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A review of stimuli-responsive nanocarriers for drug and gene delivery
Journal of Controlled Release · 2008 · 2,131 citations
Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues
Advanced Drug Delivery Reviews · 2008 · 1,734 citations
The role of PEG on the stability in digestive fluids and in vivo fate of PEG-PLA nanoparticles following oral administration
Colloids and Surfaces B Biointerfaces · 2000 · 363 citations
Barrier properties of mucus
Advanced Drug Delivery Reviews · 2008 · 1,402 citations
Micro- and macrorheology of mucus
Advanced Drug Delivery Reviews · 2009 · 1,184 citations
Measurement of gastrointestinal pH profiles in normal ambulant human subjects.
Gut · 1988 · 1,226 citations
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