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pH Directly Regulates Epidermal Permeability Barrier Homeostasis, and Stratum Corneum Integrity/Cohesion

Journal of Investigative Dermatology · 2003 · Vol. 121(2) · pp. 345–353

Jean‐Pierre Hachem✉(University of California San Francisco Medical Center)Debra Crumrine(San Francisco VA Medical Center)Joachim W. Fluhr(Friedrich Schiller University Jena)Barbara E. Brown(San Francisco VA Medical Center)Kenneth R. Feingold(San Francisco VA Medical Center)Peter M. Elias(University of California San Francisco Medical Center)

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Advancements in Transdermal Drug Delivery Ocular Surface and Contact Lens Contact Dermatitis and AllergiesStratum corneumChemistryBarrier functionBiophysicsTransepidermal water lossHomeostasisSerine proteaseDesquamationBiochemistryProtease

MeSH terms

AnimalsDesmosomesEnzyme ActivationEpidermisGuanidinesHomeostasisHydrogen-Ion ConcentrationMaleMice, HairlessPermeabilityProtonsSerine EndopeptidasesTime FactorsBridged Bicyclo Compounds, HeterocyclicRecovery of Function

Citations

523

FWCI

13.45

field-weighted impact

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100%

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