articleTop 1% cited
1-Methyl-4-phenylpyridinium ion (MPP+): Identification of a metabolite of MPTP, a toxin selective to the substantia nigra
Neuroscience Letters · 1984 · Vol. 48(1) · pp. 87–92
J. William Langston✉(Santa Clara Valley Medical Center)Ian Irwin(Santa Clara Valley Medical Center)Elizabeth B. Langston(Santa Clara Valley Medical Center)Lysia S. Forno(United States Department of Veterans Affairs)
Parkinson's Disease Mechanisms and TreatmentsBotulinum Toxin and Related Neurological DisordersAlzheimer's disease research and treatmentsMPTPSubstantia nigraNeurotoxinMetaboliteChemistryPharmacologyToxinDopamineMechanism of actionNeuroscience
MeSH terms
AnimalsBiotransformationBrainChromatography, High Pressure LiquidMalePyridinesPyridinium CompoundsSaimiriSubstantia Nigra1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine1-Methyl-4-phenylpyridinium
Citations
430
FWCI
24.20
field-weighted impact
References
13
Percentile
100%
vs. same field & year
Citations per year
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References
Selective nigral toxicity after systemic administration of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyrine (MPTP) in the squirrel monkey
Brain Research · 1984 · 918 citations
Isolation and Identification of Drugs
Journal of Clinical Pathology · 1970 · 512 citations
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1-Methyl-4-phenylpyridinium ion (MPP+): Identification of a metabolite of MPTP, a toxin selective to the substantia nigra
Neuroscience Letters · 1984 · 430 citations
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