article Open AccessTop 1% cited
Decreased expression of long noncoding RNA GAS5 indicates a poor prognosis and promotes cell proliferation in gastric cancer
BMC Cancer · 2014 · Vol. 14(1) · pp. 319–319
Ming Sun✉(Nanjing Medical University)Xin Jin(Nanjing Medical University)Rui Xia(Nanjing Medical University)Rong Kong(Nanjing Medical University)Jinhai Li(Nanjing Medical University)Tongpeng Xu(Nanjing Medical University)Yan-wen Liu(Nanjing Medical University)Erbao Zhang(Nanjing Medical University)Xiang-hua Liu(Nanjing Medical University)Wei De(Nanjing Medical University)
Abstract
Our study presents that GAS5 is significantly downregulated in gastric cancer tissues and may represent a new marker of poor prognosis and a potential therapeutic target for gastric cancer intervention.
Cancer-related molecular mechanisms researchRNA modifications and cancerCircular RNAs in diseasesGAS5CancerLong non-coding RNACancer researchCarcinogenesisBiologyCell growthCancer cellDownregulation and upregulationRNA interference
MeSH terms
AnimalsFemaleHumansMaleMice, Inbred BALB CMice, NudeMiddle AgedNeoplasm StagingStomach NeoplasmsTime FactorsTransfectionBiomarkers, TumorDown-RegulationMultivariate AnalysisChi-Square Distribution
Funding
- Government of Jiangsu Province
Citations
296
FWCI
15.20
field-weighted impact
References
32
Percentile
100%
vs. same field & year
Citations per year
References
Long noncoding RNAs: functional surprises from the RNA world
Genes & Development · 2009 · 2,363 citations
Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15INK4B tumor suppressor gene
Oncogene · 2010 · 977 citations
Minireview: Cyclin D1: Normal and Abnormal Functions
Endocrinology · 2004 · 964 citations
Long non-coding RNAs: insights into functions
Nature Reviews Genetics · 2009 · 5,773 citations
Evolution and Functions of Long Noncoding RNAs
Cell · 2009 · 5,110 citations
Epidemiology of gastric cancer
World Journal of Gastroenterology · 2006 · 2,106 citations
p21 in cancer: intricate networks and multiple activities
Nature reviews. Cancer · 2009 · 2,716 citations
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