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The PI3K/AKT/mTOR pathway as a therapeutic target in ovarian cancer

Gynecologic Oncology · 2015 · Vol. 137(1) · pp. 173–179
Seiji MabuchiHiromasa KurodaRyoko TakahashiTomoyuki Sasano
PI3K/AKT/mTOR signaling in cancerCancer Mechanisms and TherapyCRISPR and Genetic EngineeringPI3K/AKT/mTOR pathwayProtein kinase BMedicineCancer researchOvarian cancerRPTORCancerMetastasisSignal transductionInternal medicine

MeSH terms

Phosphoinositide-3 Kinase InhibitorsAnimalsFemaleHumansOvarian NeoplasmsSignal TransductionPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktTOR Serine-Threonine KinasesMolecular Targeted Therapy
Citations
409
FWCI
16.87
field-weighted impact
References
43
Percentile
99%
vs. same field & year
Citations per year
References
Targeting the phosphoinositide 3-kinase pathway in cancer
Nature Reviews Drug Discovery · 2009 · 2,742 citations
PI3K and cancer: lessons, challenges and opportunities
Nature Reviews Drug Discovery · 2014 · 1,716 citations
mTOR Signaling in Growth Control and Disease
Cell · 2012 · 8,373 citations
Cancer statistics, 2014
CA A Cancer Journal for Clinicians · 2014 · 11,558 citations
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