article Open AccessTop 10% cited

Medication adherence in HIV-infected adults

AIDS · 2004 · Vol. 18 Suppl 1 · pp. 19–25

Charles H. Hinkin✉(VA Greater Los Angeles Healthcare System)David HardyKaren MasonSteven A. CastellonRamani DurvasulaM. LamM. Stefaniak

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Abstract

Although older age is associated with higher rates of antiretroviral adherence, older participants who were cognitively impaired showed disproportionate difficulty in adequately adhering to their medication regimen. As such, efforts to detect neuropsychological dysfunction, particularly among older patients, and a thorough assessment of substance abuse, appear to be essential for the effective treatment of HIV-infected adults.

HIV/AIDS Research and Interventions HIV Research and Treatment HIV-related health complications and treatmentsMedicineNeurocognitiveNeuropsychologySubstance abuseRegimenPsychiatryLogistic regressionCohortObservational studyCohort study

MeSH terms

AdultAge FactorsAgedCocaineCognition DisordersHumansMiddle AgedNeuropsychological TestsPatient ComplianceProspective StudiesPsychomotor PerformanceHIV InfectionsDrug MonitoringSubstance-Related DisordersAntiretroviral Therapy, Highly Active

Citations

552

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10.57

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Cited by

A systematic review of the impact of alcohol use disorders on HIV treatment outcomes, adherence to antiretroviral therapy and health care utilization