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Bispectral Analysis Measures Sedation and Memory Effects of Propofol, Midazolam, Isoflurane, and Alfentanil in Healthy Volunteers
Anesthesiology · 1997 · Vol. 86(4) · pp. 836–847
Peter S. A. Glass✉(Duke University)M. Bloom(University of Pittsburgh)Lee A. KearseCarl E. RosowPeter S. SebelPaul J. Manberg
Abstract
The BIS both correlated well with the level of responsiveness and provided an excellent prediction of the loss of consciousness. These results imply that BIS may be a valuable monitor of the level of sedation and loss of consciousness for propofol, midazolam, and isoflurane.
Anesthesia and Sedative AgentsEEG and Brain-Computer InterfacesOptical Imaging and Spectroscopy TechniquesAlfentanilMedicineAnesthesiaPropofolMidazolamSedationIsofluraneBispectral indexAnestheticUnconsciousness
MeSH terms
AdultAnestheticsElectroencephalographyFemaleHumansHypnotics and SedativesIsofluraneMaleMemoryMidazolamProbabilityPropofolAlfentanil
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