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Consensus Guidelines on the Testing and Clinical Management Issues Associated With HLA and Non-HLA Antibodies in Transplantation

Transplantation · 2012 · Vol. 95(1) · pp. 19–47

Brian D. Tait(Australian Red Cross Lifeblood)Caner SüsalHoward M. Gebel(Emory University)Peter Nickerson(University of Manitoba)Andrea A. ZacharyFrans H.J. Claas(Leiden University Medical Center)Elaine F. ReedRobert A. Bray(Emory University)Patricia Campbell(University of Alberta)Jeremy R. Chapman(Westmead Hospital)P Coates(Services Australia)Robert B. Colvin(Services Australia)Emanuele Cozzi(Services Australia)Ilias I.N. Doxiadis(Leiden University Medical Center)Susan V. Fuggle(Emory University)John S. Gill(University of Manitoba)Denis Glotz(Australian Red Cross Lifeblood)Nils Lachmann(Leiden University Medical Center)Thalachallour Mohanakumar(Australian Red Cross Lifeblood)Nicole Suciu‐Foca(Australian Red Cross Lifeblood)Suchitra Sumitran–Holgersson(The University of Sydney)Kazunari Tanabe(Tokyo Women's Medical University)Craig J. Taylor(Australian Red Cross Lifeblood)Dolly B. TyanAngela C Webster(The University of Sydney)Adriana Zeevi(Emory University)Gerhard Opelz✉(University of Manitoba)

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Abstract

A comprehensive list of recommendations is provided covering the technical and pretransplantation and posttransplantation monitoring of HLA antibodies in solid organ transplantation. The recommendations are intended to provide state-of-the-art guidance in the use and clinical application of recently developed methods for HLA antibody detection when used in conjunction with traditional methods.

Renal Transplantation Outcomes and Treatments Transplantation: Methods and Outcomes Organ Transplantation Techniques and OutcomesMedicineTransplantationContext (archaeology)AntibodyHuman leukocyte antigenImmunologyLiver transplantationImmunoassayPanel reactive antibodyIntensive care medicine

MeSH terms

Complement System ProteinsCytotoxicity, ImmunologicFlow CytometryHLA AntigensHumansImmunoassayIsoantibodiesPeptide FragmentsComplement C1qComplement C4bOrgan TransplantationPractice Guidelines as Topic

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