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Copper-Catalyzed “Click” Reaction/Direct Arylation Sequence: Modular Syntheses of 1,2,3-Triazoles

Organic Letters · 2008 · Vol. 10(14) · pp. 3081–3084
Lutz AckermannHarish K. PotukuchiDirk LandsbergR. Vicente

Abstract

Inexpensive copper catalysts enabled modular one-pot multicomponent syntheses of fully decorated triazoles through a sustainable "click" reaction/direct arylation sequence.

Click Chemistry and ApplicationsChemical Synthesis and AnalysisCatalytic Cross-Coupling ReactionsChemistryCatalysisSequence (biology)Modular designCombinatorial chemistryCopperClick chemistryTriazoleCycloadditionOrganic chemistry

MeSH terms

CatalysisCopperTriazolesMolecular StructureCombinatorial Chemistry Techniques

Funding

  • Deutscher Akademischer Austauschdienst
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