articleTop 10% cited

Mitochondrial ROS govern the LPS-induced pro-inflammatory response in microglia cells by regulating MAPK and NF-κB pathways

Neuroscience Letters · 2014 · Vol. 584 · pp. 191–196

Junghyung Park(Kyungpook National University)Ju‐Sik Min(Kyungpook National University)Bokyung Kim(Kyungpook National University)Unbin Chae(Kyungpook National University)Jong Won Yun(Daegu University)Myung‐Sook Choi(Kyungpook National University)Il‐Keun Kong(Gyeongsang National University)Kyu‐Tae Chang(Korea Research Institute of Bioscience and Biotechnology)Dong‐Seok Lee✉(Kyungpook National University)

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Neuroinflammation and Neurodegeneration Mechanisms Neutrophil, Myeloperoxidase and Oxidative Mechanisms Immune Response and InflammationMicrogliaMitochondrial ROSReactive oxygen speciesCell biologyMitochondrionMAPK/ERK pathwayNADPH oxidaseInflammationNF-κBp38 mitogen-activated protein kinases

MeSH terms

AnimalsCell LineInflammationLipopolysaccharidesMitochondriaOrganophosphorus CompoundsPiperidinesSignal TransductionNF-kappa BReactive Oxygen SpeciesMicrogliaMitogen-Activated Protein KinasesExtracellular Signal-Regulated MAP Kinasesp38 Mitogen-Activated Protein KinasesMAP Kinase Kinase 4

Funding

Korea Institute of Planning and Evaluation for Technology in Food, Agriculture, Forestry and Fisheries
Korea Research Institute of Bioscience and Biotechnology
National Research Foundation of Korea

Citations

500

FWCI

11.13

field-weighted impact

References

Percentile

99%

vs. same field & year

Citations per year

Cited by

Inflammatory responses and inflammation-associated diseases in organs