article Open AccessTop 1% cited
progressiveMauve: Multiple Genome Alignment with Gene Gain, Loss and Rearrangement
PLoS ONE · 2010 · Vol. 5(6) · pp. e11147–e11147
Aaron E. Darling✉(University of Wisconsin–Madison)Bob Mau(University of Wisconsin–Madison)Nicole T. Perna(Energy Center of Wisconsin)
Abstract
The multiple genome alignments generated by our software provide a platform for comparative genomic and population genomic studies. Free, open-source software implementing the described genome alignment approach is available from http://gel.ahabs.wisc.edu/mauve.
Genomics and Phylogenetic StudiesChromosomal and Genetic VariationsProbiotics and Fermented FoodsGenomeBiologyIndelBreakpointGene duplicationGeneticsGenome evolutionComputational biologyBacterial genome sizeComparative genomics
MeSH terms
AlgorithmsModels, TheoreticalGene RearrangementSequence AlignmentGenome, Bacterial
Funding
- National Science Foundation
- U.S. Department of Health and Human Services
- National Institutes of Health
- National Institute of Allergy and Infectious Diseases
Citations
4,057
FWCI
51.53
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References
82
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References
Homology
Trends in Genetics · 2000 · 605 citations
MUSCLE: a multiple sequence alignment method with reduced time and space complexity
BMC Bioinformatics · 2004 · 9,268 citations
Mauve: Multiple Alignment of Conserved Genomic Sequence With Rearrangements
Genome Research · 2004 · 5,136 citations
OrthoMCL: Identification of Ortholog Groups for Eukaryotic Genomes
Genome Research · 2003 · 6,112 citations
Versatile and open software for comparing large genomes
Genome biology · 2004 · 5,792 citations
Aligning Multiple Genomic Sequences With the Threaded Blockset Aligner
Genome Research · 2004 · 1,579 citations
The Pangenome Structure of<i>Escherichia coli</i>: Comparative Genomic Analysis of<i>E. coli</i>Commensal and Pathogenic Isolates
Journal of Bacteriology · 2008 · 859 citations
ProbCons: Probabilistic consistency-based multiple sequence alignment
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