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Nanoceria exhibit redox state-dependent catalase mimetic activity

Chemical Communications · 2010 · Vol. 46(16) · pp. 2736–2736
Talib PirmohamedJanet M. DowdingSanjay SinghBrian WassermanEric HeckertAjay KarakotiJessica E. S. KingSudipta SealWilliam T. Self

Abstract

In this study we have found that cerium oxide nanoparticles exhibit catalase mimetic activity. Surprisingly, the catalase mimetic activity correlates with a reduced level of cerium in the +3 state, in contrast to the relationship between surface charge and superoxide scavenging properties.

Advanced Nanomaterials in CatalysisCarbon and Quantum Dots ApplicationsElectrochemical sensors and biosensorsCatalaseCeriumCerium oxideChemistryRedoxOxidation stateSuperoxideSuperoxide dismutaseInorganic chemistryPhotochemistry

MeSH terms

CatalaseCeriumOxidation-ReductionFree Radical ScavengersBiomimeticsNanoparticles
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References
Mitochondrial free radical generation, oxidative stress, and aging
Free Radical Biology and Medicine · 2000 · 2,948 citations
Neurodegenerative diseases and oxidative stress
Biomedicine & Pharmacotherapy · 2003 · 1,020 citations
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