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Tumor-associated macrophages promote cancer stem cell-like properties via transforming growth factor-beta1-induced epithelial–mesenchymal transition in hepatocellular carcinoma

Cancer Letters · 2014 · Vol. 352(2) · pp. 160–168
Qingmin FanYingying JingGuofeng YuXingrui KouFei YeLu GaoRong LiQiudong ZhaoYang YangZhenghua LuLixin Wei
Immune cells in cancerCancer Cells and MetastasisEpigenetics and DNA MethylationCancer researchCancer stem cellCD68Tumor-associated macrophageEpithelial–mesenchymal transitionTumor microenvironmentHepatocellular carcinomaTransforming growth factorMesenchymal stem cellMetastasis

MeSH terms

Epithelial Cell Adhesion MoleculeCD68 MoleculeAdultAgedAnimalsAntigens, NeoplasmCell MovementFemaleCarcinoma, HepatocellularHumansLiver NeoplasmsMacrophagesMaleMiddle AgedNeoplasm Invasiveness

Funding

  • National Natural Science Foundation of China
  • Science and Technology Commission of Shanghai Municipality
  • Shanghai Municipal Health Bureau
Citations
453
FWCI
16.12
field-weighted impact
References
45
Percentile
99%
vs. same field & year
Citations per year
References
Vimentin in cancer and its potential as a molecular target for cancer therapy
Cellular and Molecular Life Sciences · 2011 · 1,569 citations
Global Cancer Statistics, 2002
CA A Cancer Journal for Clinicians · 2005 · 18,373 citations
TGF-β in progression of liver disease
Cell and Tissue Research · 2011 · 705 citations
Global cancer statistics
CA A Cancer Journal for Clinicians · 2011 · 55,006 citations
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