article Open AccessTop 10% cited
The M1 form of tumor-associated macrophages in non-small cell lung cancer is positively associated with survival time
BMC Cancer · 2010 · Vol. 10(1) · pp. 112–112
Junliang Ma✉(Sichuan University)Lunxu Liu(West China Hospital of Sichuan University)Guowei Che(Sichuan University)Nanbin Yu(West China Hospital of Sichuan University)Fuqiang Dai(West China Hospital of Sichuan University)Zongbing You(Tulane University)
Abstract
The M1 macrophage density in the tumor islets is an independent predictor of survival time in NSCLC patients.
Immune cells in cancerEpigenetics and DNA MethylationCancer Immunotherapy and BiomarkersCD68Tumor-associated macrophageCD163StromaMacrophageSurgical oncologyMedicineLung cancerImmunohistochemistryM2 Macrophage
MeSH terms
CD68 MoleculeCD163 AntigenAgedCarcinoma, Non-Small-Cell LungFemaleHLA-DR AntigensHumansLung NeoplasmsMacrophagesMaleMiddle AgedReceptors, Cell SurfaceRetrospective StudiesTime FactorsAntigens, Differentiation, Myelomonocytic
Funding
- U.S. Department of Defense
- Sichuan University
- National Institutes of Health
- West China Hospital, Sichuan University
- Fogarty International Center
- National Center for Research Resources
Citations
434
FWCI
7.08
field-weighted impact
References
22
Percentile
98%
vs. same field & year
Citations per year
Cited by
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References
Revisions in the International System for Staging Lung Cancer
CHEST Journal · 1997 · 4,599 citations
Alternative activation of macrophages
Nature reviews. Immunology · 2003 · 6,118 citations
Inflammation and cancer: back to Virchow?
The Lancet · 2001 · 7,614 citations
Distinct Role of Macrophages in Different Tumor Microenvironments
Cancer Research · 2006 · 2,202 citations
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