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The Impact of Recanalization on Ischemic Stroke Outcome
Stroke · 2007 · Vol. 38(3) · pp. 967–973
Joung‐Ho Rha✉(Inha University Hospital)Jeffrey L. Saver(Inha University Hospital)
Abstract
Formal meta-analysis confirms a strong correlation between recanalization and outcome in acute ischemic stroke. Recanalization is strongly associated with improved functional outcomes and reduced mortality. These findings suggest that recanalization is an appropriate biomarker of therapeutic activity in early phase trials of thrombolytic treatment in acute ischemic stroke.
Acute Ischemic Stroke ManagementVenous Thromboembolism Diagnosis and ManagementCerebrovascular and Carotid Artery DiseasesMedicineOdds ratioInternal medicineStroke (engine)Fibrinolytic agentMeta-analysisThrombolysisSurrogate endpointCardiologyClinical trial
MeSH terms
Cerebral ArteriesBrain IschemiaClinical Trials as TopicHumansThrombolytic TherapyTreatment OutcomeStroke
Funding
- Eli Lilly and Company
- National Institutes of Health
Citations
1,445
FWCI
32.33
field-weighted impact
References
74
Percentile
100%
vs. same field & year
Citations per year
Cited by
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References
Recombinant tissue plasminogen activator in acute thrombotic and embolic stroke
Annals of Neurology · 1992 · 1,002 citations
Safety and Efficacy of Mechanical Embolectomy in Acute Ischemic Stroke
Stroke · 2005 · 1,313 citations
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