articleTop 1% cited
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
Nature Cell Biology · 2010 · Vol. 12(2) · pp. 119–131
Sven Geisler✉Kira M. Holmström(University of Tübingen)Diana Skujat(University of Tübingen)Fabienne C. Fiesel(University of Tübingen)Oliver C. Rothfuss(University of Tübingen)Philipp J. Kahle(Hertie Institute for Clinical Brain Research)Wolfdieter Springer(Hertie Institute for Clinical Brain Research)
Autophagy in Disease and TherapyParkinson's Disease Mechanisms and TreatmentsUbiquitin and proteasome pathwaysParkinPINK1MitophagyVDAC1AutophagyUbiquitin ligaseCell biologyUbiquitinMitochondrionBiology
MeSH terms
Sequestosome-1 ProteinPTEN-Induced Putative KinaseAutophagyBiological TransportFluorescent Antibody TechniqueHeLa CellsHumansMitochondriaMutationParkinson DiseaseProtein KinasesImmunoblottingRNA InterferenceUbiquitin-Protein LigasesCell Line, Tumor
Citations
2,752
FWCI
116.70
field-weighted impact
References
40
Percentile
100%
vs. same field & year
Citations per year
Cited by
Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling
Biochemical Journal · 2011 · 1,414 citations
Multiple Roles of the Small GTPase Rab7
Cells · 2016 · 392 citations
The Ubiquitin Code
Annual Review of Biochemistry · 2012 · 3,574 citations
Mitochondrial dysfunction in the pathophysiology of renal diseases
American Journal of Physiology-Renal Physiology · 2013 · 376 citations
Regulation of autophagy by mTOR-dependent and mTOR-independent pathways: autophagy dysfunction in neurodegenerative diseases and therapeutic application of autophagy enhancers
Biochemical Society Transactions · 2013 · 363 citations
Mechanisms of mitophagy
Nature Reviews Molecular Cell Biology · 2010 · 3,157 citations
Regulation of autophagy by ROS: physiology and pathology
Trends in Biochemical Sciences · 2010 · 1,243 citations
The Beclin 1 network regulates autophagy and apoptosis
Cell Death and Differentiation · 2011 · 2,468 citations
References
Mitochondrial Membrane Permeabilization in Cell Death
Physiological Reviews · 2007 · 3,546 citations
p62/SQSTM1 Binds Directly to Atg8/LC3 to Facilitate Degradation of Ubiquitinated Protein Aggregates by Autophagy
Journal of Biological Chemistry · 2007 · 4,501 citations
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
The Journal of Cell Biology · 2005 · 3,224 citations
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
The Journal of Cell Biology · 2008 · 3,925 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.
