articleTop 1% cited
Transition‐Metal‐Mediated Routes to 3,3‐Disubstituted Oxindoles through Anilide Cyclisation
European Journal of Organic Chemistry · 2011 · Vol. 2011(34) · pp. 6821–6841
Johannes E. M. N. Klein✉(University of York)Richard J. K. Taylor(University of York)
Abstract
Abstract This review describes transition‐metal‐catalysed and ‐mediated processes for the preparation of oxindoles from anilides through C(3)–C(3a) bond formation. Traditional methods, such as the Heck reaction, and recent developments, including direct Ar–H coupling processes, are presented, as are applications in natural product synthesis.
Catalytic C–H Functionalization MethodsCatalytic Cross-Coupling ReactionsAsymmetric Hydrogenation and CatalysisChemistryTransition metalCombinatorial chemistryPalladiumNatural productHeck reactionOrganic chemistryStereochemistryCatalysis
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References
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