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Antidepressants increase neural progenitor cells in the human hippocampus

Neuropsychopharmacology · 2009 · Vol. 34(11) · pp. 2376–2389
Maura BoldriniMark D. UnderwoodRené HenGorazd RosoklijaAndrew J. DworkJ. John MannVictoria Arango
Neurogenesis and neuroplasticity mechanismsNeuroscience and Neuropharmacology ResearchMemory and Neural MechanismsNeuNDentate gyrusMajor depressive disorderNeurogenesisNeural stem cellAntidepressantInternal medicineProgenitor cellEndocrinologyTricyclic

MeSH terms

AdolescentAdultAgingAntidepressive AgentsAntidepressive Agents, TricyclicCell DivisionDepressive Disorder, MajorMajor Depressive DisorderFemaleHumansMaleMiddle AgedNeuronsOrgan SizeSex Characteristics

Funding

  • American Foundation for Suicide Prevention
Citations
668
FWCI
20.77
field-weighted impact
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83
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100%
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References
The Stanley Foundation brain collection and Neuropathology Consortium
Schizophrenia Research · 2000 · 534 citations
Unbiased stereological estimation of the number of neurons in the human hippocampus
The Journal of Comparative Neurology · 1990 · 1,152 citations
Vascular niche for adult hippocampal neurogenesis
The Journal of Comparative Neurology · 2000 · 1,815 citations
Hippocampal Volume Reduction in Major Depression
American Journal of Psychiatry · 2000 · 1,660 citations
Neurogenesis in the adult human hippocampus
Nature Medicine · 1998 · 6,280 citations
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Antidepressants increase neural progenitor cells in the human hippocampus · Scinovex