article Open AccessTop 1% cited
Increasing Adult Hippocampal Neurogenesis is Sufficient to Reduce Anxiety and Depression-Like Behaviors
Neuropsychopharmacology · 2015 · Vol. 40(10) · pp. 2368–2378
Alexis S. Hill(Columbia University)Amar Sahay✉(Massachusetts General Hospital)René Hen(Columbia University)
Neurogenesis and neuroplasticity mechanismsNerve injury and regenerationAxon Guidance and Neuronal SignalingNeurogenesisHippocampal formationCorticosteroneHippocampusPsychologyAnxietyNeuroscienceNeural stem cellEndocrinologyMedicine
MeSH terms
Doublecortin Domain ProteinsAnimalsAnxietyBromodeoxyuridineCorticosteroneDepressionDisease Models, AnimalExploratory BehaviorHippocampusHypothalamo-Hypophyseal SystemMice, Inbred C57BLMice, TransgenicMicrotubule-Associated ProteinsNeuropeptidesPituitary-Adrenal System
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References
Exercise Enhances Learning and Hippocampal Neurogenesis in Aged Mice
Journal of Neuroscience · 2005 · 2,069 citations
Effects of Chronic Fluoxetine in Animal Models of Anxiety and Depression
Neuropsychopharmacology · 2004 · 664 citations
Antidepressants increase neural progenitor cells in the human hippocampus
Neuropsychopharmacology · 2009 · 668 citations
Are the Dorsal and Ventral Hippocampus Functionally Distinct Structures?
Neuron · 2010 · 3,329 citations
Transient expression of doublecortin during adult neurogenesis
The Journal of Comparative Neurology · 2003 · 1,508 citations
Neurogenesis in the Dentate Gyrus of the Adult Tree Shrew Is Regulated by Psychosocial Stress and NMDA Receptor Activation
Journal of Neuroscience · 1997 · 1,477 citations
Chronic Antidepressant Treatment Increases Neurogenesis in Adult Rat Hippocampus
Journal of Neuroscience · 2000 · 3,090 citations
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