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Continuous cultures of fused cells secreting antibody of predefined specificity

Nature · 1975 · Vol. 256(5517) · pp. 495–497
Georges KöhlerCésar Milstein
Glycosylation and Glycoproteins ResearchMonoclonal and Polyclonal Antibodies ResearchViral Infectious Diseases and Gene Expression in InsectsAntibodySpleenCell cultureMonoclonal antibodyCell fusionMultiple myelomaSecretionMolecular biologyCellTissue culture

MeSH terms

AnimalsAntibody FormationAntibody SpecificityCell FusionCell LineErythrocytesGenetic CodeImmunoglobulinsMice, Inbred BALB CMultiple MyelomaSpleenCulture TechniquesMice
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References
Progress in immunology
The Journal of Pediatrics · 1968 · 577 citations
Mouse myelomas and lymphomas in culture
Experimental Cell Research · 1970 · 552 citations
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