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Pericytes and Perivascular Fibroblasts Are the Primary Source of Collagen-Producing Cells in Obstructive Fibrosis of the Kidney

American Journal Of Pathology · 2008 · Vol. 173(6) · pp. 1617–1627
Shuei‐Liong LinTatiana KisselevaDavid A. BrennerJeremy S. Duffield
Renal and related cancersChronic Kidney Disease and DiabetesTissue Engineering and Regenerative MedicineFibrosisPathologyKidneyPrimary (astronomy)ChemistryCell biologyMedicineBiologyInternal medicinePhysics

MeSH terms

Snail Family Transcription FactorsCollagen Type I, alpha 1 ChainAnimalsCell DifferentiationChimeraDisease Models, AnimalFibroblastsFibrosisKidneyMice, Inbred C57BLMice, TransgenicRecombinant Fusion ProteinsTranscription FactorsBiomarkersPericytes

Funding

  • American Society of Nephrology
  • National Science Council
  • National Institutes of Health
  • University of California, San Diego
Citations
834
FWCI
17.65
field-weighted impact
References
56
Percentile
100%
vs. same field & year
Citations per year
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References
Evidence that fibroblasts derive from epithelium during tissue fibrosis
Journal of Clinical Investigation · 2002 · 1,813 citations
Endothelial/Pericyte Interactions
Circulation Research · 2005 · 2,013 citations
Direct regulation of TWIST by HIF-1α promotes metastasis
Nature Cell Biology · 2008 · 1,329 citations
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