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Blood Transfusion, Independent of Shock Severity, Is Associated with Worse Outcome in Trauma

The Journal of Trauma: Injury, Infection, and Critical Care · 2003 · Vol. 54(5) · pp. 898–907

Debra L. Malone✉(University of Maryland, Baltimore)James R. Dunne(University of Maryland, Baltimore)J. Kathleen Tracy(University of Maryland, Baltimore)A. Tyler Putnam(University of Maryland, Baltimore)Thomas M. Scalea(University of Maryland, Baltimore)Lena M. Napolitano(University of Maryland, Baltimore)

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Abstract

Blood transfusion is confirmed as an independent predictor of mortality, ICU admission, ICU LOS, and hospital LOS in trauma after controlling for severity of shock by admission base deficit, lactate, shock index, and anemia. The use of other hemoglobin-based oxygen-carrying resuscitation fluids (such as human or bovine hemoglobin substitutes) in the acute postinjury period warrants further investigation.

Trauma, Hemostasis, Coagulopathy, Resuscitation Trauma and Emergency Care Studies Blood transfusion and managementMedicineGlasgow Coma ScaleIntensive care unitInjury Severity ScoreBlood pressureHematocritOdds ratioConfidence intervalBlood transfusionShock (circulatory)

MeSH terms

AdultAnemiaBlood TransfusionFemaleHumansIntensive Care UnitsLength of StayMalePatient AdmissionPrognosisProspective StudiesRisk FactorsShockWounds and InjuriesGlasgow Coma Scale

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619

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19.47

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Cited by

Management of bleeding following major trauma: an updated European guideline