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Characterization of the binding of 3H-SCH 23390, a selective D-1 receptor antagonist ligand, in rat striatum

Life Sciences · 1984 · Vol. 35(18) · pp. 1885–1893
Receptor Mechanisms and SignalingNeuropeptides and Animal PhysiologyNeurotransmitter Receptor Influence on BehaviorSCH-23390SpiperoneChemistryRadioligandDopamine receptorDopamine antagonistReceptorLigand (biochemistry)AntagonistBinding site

MeSH terms

AnimalsBenzazepinesBinding, CompetitiveCorpus StriatumKineticsMaleRats, Inbred StrainsReceptors, DopamineSpiperoneStructure-Activity RelationshipRats
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565
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19.81
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13
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References
SCH 23390—The first selective dopamine D-1 antagonist
European Journal of Pharmacology · 1983 · 738 citations
SCH 23390, a potential benzazepine antipsychotic with unique interactions on dopaminergic systems.
Journal of Pharmacology and Experimental Therapeutics · 1983 · 897 citations
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