review Open AccessTop 10% cited
A systematic review of the use of opioids in the management of dyspnoea
Thorax · 2002 · Vol. 57(11) · pp. 939–944
A-L Jennings✉(Barnet and Chase Farm NHS Hospitals Trust)
Abstract
This review supports the continued use of oral and parenteral opioids to treat dyspnoea in patients with advanced disease. There are insufficient data from the meta-analysis to conclude whether nebulised opioids are effective, but the results from included studies that did not contribute to the meta-analysis suggest that they are no better than nebulised normal saline.
Chronic Obstructive Pulmonary Disease (COPD) ResearchRespiratory Support and MechanismsObstructive Sleep Apnea ResearchMedicineMeta-analysisCOPDPlaceboSubgroup analysisSystematic reviewMeta-regressionIntensive care medicineMEDLINEInternal medicine
MeSH terms
Administration, OralDouble-Blind MethodDyspneaHumansInfusions, ParenteralNarcoticsRegression AnalysisRandomized Controlled Trials as TopicPulmonary Disease, Chronic Obstructive
Funding
- Imperial College London
- Medical Research Council
Citations
638
FWCI
11.44
field-weighted impact
References
34
Percentile
99%
vs. same field & year
Citations per year
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References
A random‐effects regression model for meta‐analysis
Statistics in Medicine · 1995 · 905 citations
Meta-analyses involving cross-over trials: methodological issues
International Journal of Epidemiology · 2002 · 2,281 citations
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