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Distribution and Tissue Uptake of Poly(ethylene glycol) with Different Molecular Weights after Intravenous Administration to Mice

Journal of Pharmaceutical Sciences · 1994 · Vol. 83(4) · pp. 601–606
Tetsuji YamaokaYasuhiko TabataYoshito Ikada
Orthopaedic implants and arthroplastyRadiopharmaceutical Chemistry and ApplicationsPharmacological Effects and Toxicity StudiesPEG ratioEthylene glycolChemistryPharmacokineticsMolecular massDistribution (mathematics)Vascular permeabilityPermeability (electromagnetism)Molar mass distributionPharmacology

MeSH terms

AnimalsFemaleHalf-LifeInjections, IntravenousIodine RadioisotopesKupffer CellsMice, Inbred BALB CModels, BiologicalMolecular WeightPolyethylene GlycolsTissue DistributionMacrophages, PeritonealMiceRatsIn Vitro Techniques
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729
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97%
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Distribution and Tissue Uptake of Poly(ethylene glycol) with Different Molecular Weights after Intravenous Administration to Mice · Scinovex