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Intravenous hMSCs Improve Myocardial Infarction in Mice because Cells Embolized in Lung Are Activated to Secrete the Anti-inflammatory Protein TSG-6

Cell stem cell · 2009 · Vol. 5(1) · pp. 54–63
Ryang Hwa LeeА. А ПулинMin Jeong SeoDaniel J. KotaJoni YlöstaloBenjamin L. LarsonLaura Semprun‐PrietoPatrice DelafontaineDarwin J. Prockop
Mesenchymal stem cell researchTissue Engineering and Regenerative MedicineCongenital heart defects researchMesenchymal stem cellLungMyocardial infarctionBiologySecretionDownregulation and upregulationInflammationStromal cellCancer researchImmunology

MeSH terms

AnimalsHeartHumansInfusions, IntravenousLungMyocardial InfarctionPulmonary EmbolismCell Adhesion MoleculesStromal CellsInflammation MediatorsGene Expression ProfilingMultipotent Stem CellsMiceCell Migration Assays

Funding

  • National Institutes of Health
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