articleTop 1% cited

Microglial-produced nitric oxide and reactive nitrogen oxides mediate neuronal cell death

Brain Research · 1992 · Vol. 587(2) · pp. 250–256

Kathleen M.K. Boje✉Prince K. Arora(National Institute of Diabetes and Digestive and Kidney Diseases)

Neuroinflammation and Neurodegeneration Mechanisms Neurological Disease Mechanisms and Treatments Nitric Oxide and Endothelin EffectsNeurotoxicityMicrogliaSuperoxideNitric oxideReactive oxygen speciesReactive nitrogen speciesChemistryNitric oxide synthaseSuperoxide dismutaseNMDA receptor

MeSH terms

Amino Acid OxidoreductasesAnimalsArginineCells, CulturedCerebellumFemaleImmunizationImmunohistochemistryNeurogliaNitric OxideNitritesNitrogen OxidesPregnancyRats, Inbred StrainsReceptors, N-Methyl-D-Aspartate

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Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide.

Proceedings of the National Academy of Sciences · 1987 · 5,041 citations

Microglial-produced nitric oxide and reactive nitrogen oxides mediate neuronal cell death

Brain Research · 1992 · 942 citations

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