articleTop 1% cited
From calcium signaling to cell death: two conformations for the mitochondrial permeability transition pore. Switching from low- to high-conductance state
Biochimica et Biophysica Acta (BBA) - Bioenergetics · 1998 · Vol. 1366(1-2) · pp. 33–50
François Ichas✉(University of Padua)Jean-Pierre Mazat(Inserm)
Mitochondrial Function and PathologyATP Synthase and ATPases ResearchLipid Membrane Structure and BehaviorThapsigarginConductanceBiophysicsChemistryCell biologyMitochondrial permeability transition poreProgrammed cell deathCalcium signalingVoltage-dependent anion channelMitochondrion
MeSH terms
AnimalsCalciumEndoplasmic ReticulumIntracellular MembranesMembrane PotentialsMitochondriaPermeabilityProtein ConformationCalcium ChannelsSignal TransductionCell DeathApoptosis
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References
Mechanisms by which mitochondria transport calcium
American Journal of Physiology-Cell Physiology · 1990 · 1,634 citations
The Ca2+-induced membrane transition in mitochondria
Archives of Biochemistry and Biophysics · 1979 · 772 citations
The Ca2+-induced membrane transition in mitochondria
Archives of Biochemistry and Biophysics · 1979 · 848 citations
Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization
The EMBO Journal · 1998 · 1,231 citations
Intracellular Adenosine Triphosphate (ATP) Concentration: A Switch in the Decision Between Apoptosis and Necrosis
The Journal of Experimental Medicine · 1997 · 1,859 citations
Induction of Apoptotic Program in Cell-Free Extracts: Requirement for dATP and Cytochrome c
Cell · 1996 · 5,154 citations
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