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Comparative Affinity of Duloxetine and Venlafaxine for Serotonin and Norepinephrine Transporters in vitro and in vivo, Human Serotonin Receptor Subtypes, and Other Neuronal Receptors

Neuropsychopharmacology · 2001 · Vol. 25(6) · pp. 871–880
Frank P. Bymaster
Neurotransmitter Receptor Influence on BehaviorReceptor Mechanisms and SignalingNeuroscience and Neuropharmacology ResearchDuloxetineVenlafaxineSerotoninReuptake inhibitorSerotonin transporterPharmacologyIn vivoChemistryReuptakeSerotonin Plasma Membrane Transport Proteins

MeSH terms

Duloxetine HydrochlorideVenlafaxine HydrochlorideAnimalsCarrier ProteinsCell LineCyclohexanolsDose-Response Relationship, DrugHumansMaleMembrane GlycoproteinsMonoamine OxidaseNerve Tissue ProteinsNeuronsp-ChloroamphetamineRadioligand Assay
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Comparative Affinity of Duloxetine and Venlafaxine for Serotonin and Norepinephrine Transporters in vitro and in vivo, Human Serotonin Receptor Subtypes, and Other Neuronal Receptors · Scinovex