review Open AccessTop 1% cited
The immunological and genetic basis of inflammatory bowel disease
Nature reviews. Immunology · 2003 · Vol. 3(7) · pp. 521–533
Gerd Bouma✉(National Institutes of Health)Warren Strober(National Institutes of Health)
Inflammatory Bowel DiseaseIL-33, ST2, and ILC PathwaysReproductive System and PregnancyNOD2Ulcerative colitisInflammatory bowel diseaseDiseasePathogenesisImmunologyCrohn's diseaseMedicineGastrointestinal tractInflammatory Bowel Diseases
MeSH terms
AnimalsCarrier ProteinsDisease Models, AnimalHumansImmune ToleranceMutationInflammatory Bowel DiseasesCytokinesTh1 CellsTh2 CellsGenetic Predisposition to DiseaseIntracellular Signaling Peptides and ProteinsMiceNod2 Signaling Adaptor Protein
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References
Hapten-Induced Model of Chronic Inflammation and Ulceration in the Rat Colon
Gastroenterology · 1989 · 1,709 citations
Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide
Nature Immunology · 2001 · 1,632 citations
Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells
Nature Immunology · 2010 · 5,839 citations
A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice
Gastroenterology · 1990 · 2,404 citations
Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn’s disease LP cells manifest increased secretion of IFN-γ, whereas ulcerative colitis LP cells manifest increased secretion of IL-5
The Journal of Immunology · 1996 · 1,228 citations
Control of Regulatory T Cell Development by the Transcription Factor <i>Foxp3</i>
Science · 2003 · 8,062 citations
Impaired On/Off Regulation of TNF Biosynthesis in Mice Lacking TNF AU-Rich Elements
Immunity · 1999 · 1,351 citations
Stimulation of CD25+CD4+ regulatory T cells through GITR breaks immunological self-tolerance
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